Hard pimples are considered to be related to acne and boils, and general treatment and medication are recommended to improve the condition. 1. Acne: Acne may cause pimples, so it is recommended to have a regular routine and take oral medication such as isotretinoin under doctor’s supervision. Combined topical antibiotic medications such as fusidic acid and clindamycin can also be used to promote recovery. 2. Boils: Boils may also appear as hard lumps of acne, patients should not scratch and squeeze the affected area, it is recommended to follow the doctor’s instructions to use tincture of iodine and other drugs to help disinfect and sterilize. If the lesions are large or recurring, it is necessary to take oral ceftazidime, amoxicillin and other antibiotics under the guidance of the doctor to promote the receding of the rash. There are many causes of hardened acne, so it is recommended that patients seek medical examination to clarify the cause of the disease and cooperate with the doctor for standardized treatment.