Cluster headache nemesis this statement is not scientific, cluster headache should be given under the guidance of specialists in scientific and reasonable treatment, including acute treatment and preventive treatment. 1. Acute treatment: including oxygen therapy and tretinoin treatment. Inhalation of 100% pure oxygen can effectively terminate headache attacks, but it is not recommended for patients with chronic obstructive pulmonary disease. Tretinoin can be used as a complementary treatment, adverse effects include headache and dizziness, gastrointestinal reactions, etc. It is contraindicated in patients with ischemic heart disease. 2. Prophylaxis: Verapamil is the drug of choice for the prevention of episodic and chronic cluster headache. Adverse effects include constipation, dizziness, hypotension, peripheral edema, bradycardia, etc. Verapamil is contraindicated in patients with severe left heart insufficiency, hypotension and cardiogenic shock. Cluster headache should be standardized treatment under the guidance of a physician, the so-called nemesis is not scientific, it is recommended that patients should seek medical attention if they are unwell.