Small-focal high-grade papillary uroepithelial carcinoma of the bladder is generally more serious and needs to be treated by surgery in time to prevent the cancer cells from spreading and metastasizing. High-grade papillary uroepithelial carcinoma of small foci of the bladder is generally more malignant and prone to invasion, progression and metastasis, and may present with symptoms such as painless hematuria, urinary frequency and urinary pain, so the severity is much higher than that of common bladder cancer. Small focal high-grade papillary uroepithelial carcinoma of the bladder, if in early stage, can be removed by radical surgery, and pelvic lymph node dissection surgery after surgery. If metastasis of cancer cells has occurred, chemotherapy and radiotherapy are more often used to alleviate the condition and prolong the survival period. Keep a good mindset, don’t have too much psychological pressure, do a good job in patient’s psychological communication, pay attention to nutritional supplementation, prohibit smoking and alcohol, eat more fresh fruits and vegetables, and pay attention to rest.