First, acute hepatitis can cause splenomegaly and portal hypertension. Secondly, it is usually possible to recover from splenomegaly and portal hypertension caused by acute hepatitis if the symptoms are not severe and are treated promptly. Acute hepatitis refers to low-grade fever, generalized weakness and other symptoms caused by viruses, bacteria, alcohol and other factors that attack the liver, resulting in liver cell damage and necrosis and impaired liver function. Due to the rapid onset of acute hepatitis, it can cause a sharp decline in liver function within a short period of time, severe hepatocellular edema, squeezing the hepatic blood sinusoids to make the venous blood reflux unsatisfactory, resulting in splenomegaly, portal hypertension and other symptoms. Acute hepatitis can be treated symptomatically, such as fever, vomiting, fever, antiemetic, rehydration and other treatments; dicyclomine and other medications to protect the liver and reduce the role of enzymes; if the virus causes acute hepatitis, choose entecavir and other drugs for antiviral therapy. All of the above drugs should be used under the guidance of the doctor and should not be used without authorization. Patients with acute hepatitis should seek medical treatment in time to clarify the diagnosis and carry out targeted treatment.