Taking estrogen can be taken at the same time as epirubicin hydrochloride, celecoxib capsules and levamlodipine tablets, and there is no contraindication to the compounding of the above drugs. 1. Estrogen tablets are suitable for the treatment of vasodilatation symptoms associated with menopause, vulvar and vaginal atrophy, control and prevention of osteoporosis, breast cancer and prostate cancer adjuvant therapy; adverse reactions include breast enlargement, fluid overflow, hair loss, arthralgia, weight change, etc., and is contraindicated in the treatment of undiagnosed genital hemorrhage, deep vein thrombosis, pulmonary embolism, and hepatic function abnormalities. 2. Eperisone is suitable for neck, shoulder, waist and back pain, spasmodic paralysis, post-traumatic sequelae, etc. Adverse reactions include rash, insomnia, gastrointestinal reactions, tremor, etc. It is contraindicated in patients with severe hepatic and renal insufficiency and shock. Celecoxib is suitable for symptomatic treatment of arthritis and acute pain, adverse reactions include gastrointestinal reactions, hypertension exacerbation, etc. It is prohibited in patients with gastrointestinal bleeding, severe heart failure, and allergy to sulfonamides. 3. Zuo Yi that is, levamlodipine is suitable for the treatment of essential hypertension, adverse reactions include rash, edema, flushing, etc. It is prohibited for those who are allergic to the drug. Estrogen and epirubicin, celecoxib, levitra can be taken together without contraindications, it is recommended that patients should use the drug under the guidance of a physician, do not blindly self-medication.