Although there is no clear contraindication to taking febuxostat, febuxostat is used for the treatment of hyperuricemia combined with gout, and alcohol consumption is not recommended for this disease. Alcohol contains ethanol and purine substances, which can easily affect purine metabolism and lead to elevated blood uric acid. Therefore, people with hyperuricemia should not drink alcohol, which can easily trigger gout and lead to joint pain. Febuxostat is a uric acid-lowering drug that can be used to treat patients with hyperuricemia combined with gout, and it is recommended that gout patients should not drink alcohol. It should be noted that, during the drug may appear loss of appetite, nausea, abdominal distension and other adverse reactions, if the components of febuxostat allergy, or accept azathioprine treatment can not use the drug. Patients are advised to go to the rheumatology and immunology departments of regular hospitals for detailed consultation and follow the doctor’s instructions to standardize the use of medication.