Apical inflammation is generally referred to as periapical inflammation, the disease is usually not recommended to use drug treatment, if there is a serious infection, you can use metronidazole for anti-infection treatment. Periapical infection is related to bacterial infection, may be secondary to dental caries, endodontics and other diseases, the symptoms of infection is more serious can be treated with metronidazole, the drug has antibacterial effect, can be used for anaerobic bacteria infection caused by the disease. Periapical periodontitis is usually treated by endodontics, which mainly involves the use of medication to sterilize the root canal and then repair it with root canal filling, which can help to control the infection and prevent further deterioration of apical diseases, and in severe cases, it can also be treated by apicoectomy and tooth extraction. It is recommended that patients seek timely medical treatment and strictly follow the doctor’s instructions for medication.