Glomerulonephritis has relatively many factors affecting the prognosis, mainly including the type of pathology, the amount of urinary protein, the level of blood pressure, the patient’s response to medication, the patient’s adherence, and dietary control. 1. The type of pathology has a great impact on the prognosis of glomerulonephritis. Some pathologies are mild and the prognosis of patients is good, such as mild thylakoid proliferative glomerulonephritis; some nephritis has a relatively poor prognosis, such as membranoproliferative glomerulonephritis. 2. The amount of urine protein and blood pressure affect the prognosis of glomerulonephritis, the more protein and the higher blood pressure, the worse the prognosis of the patient, and the higher the possibility of progressing to uremia. 3. Different patients have different responses to drugs, those who respond well to drugs have relatively better prognosis; if they respond poorly to drugs, especially glucocorticoids and other immunological agents, the prognosis of patients is relatively poor. 4. Patient compliance and dietary control also have a greater impact on the prognosis, strict low-salt, high-quality and low-protein diet will slow down the decline of renal function. It is recommended that patients with glomerulonephritis should go to the hospital in time, complete the relevant examinations under the guidance of the doctor, and guide the treatment, so as not to delay the condition.