Unilateral knee replacement usually costs $50,000~$100,000, which is related to the prosthesis manufacturer, prosthesis material, region, etc. It is recommended to consult the local hospital. For knee osteoarthritis, rheumatoid arthritis, traumatic arthritis, bone ischemic necrosis and other diseases, when the patient’s condition is serious and causes instability, stiffness or deformity of the knee joint, the patient can seek medical treatment through knee replacement. The total cost of knee replacement usually ranges from $50,000 to $100,000, depending on the price of the prosthesis. Generally, the cost of domestic or mid-range prosthesis is around 30,000~50,000 dollars. However, if you choose an imported, high-grade prosthesis, the cost will be around 50,000~70,000 dollars. In addition to the cost of the prosthesis, the cost of preoperative examination, anesthesia, surgery, various postoperative treatments and nursing costs should also be considered. Patients should consult regular hospitals for knee replacement surgery, and should actively cooperate with doctors for rehabilitation training, so as to promote the return of normal knee function as soon as possible. It is recommended that patients choose the appropriate prosthesis according to their own financial situation and seek advice from their doctors, and the reimbursement rate varies from place to place, so the specific costs should be consulted with the local hospital. The country will introduce a collective procurement policy in the future, and after the implementation of the policy, the price will drop significantly.