The liver is mainly located in the right quarter rib area and the upper abdominal area, most of the liver is covered by the rib arch, only in the upper abdominal area, the right subcostal exposure and direct contact with the anterior abdominal wall, and above the liver with the diaphragm and the anterior abdominal wall. Pain in the hepatic region is not a separate disease, but a group of symptoms with a complex etiology. Hepatobiliary system diseases, trauma, lung diseases, chest wall diseases, etc. may cause pain in the liver area, and other diseases that can cause abdominal pain, such as intestinal obstruction, intestinal perforation, peritonitis, etc. may also cause pain in the liver area. Persistent pain in the liver area, especially with symptoms such as jaundice, spider nevus, liver palms, liver and spleen enlargement, or accompanied by a mass in the right upper abdomen, fever, chills, fatigue, lethargy, loss of appetite, etc., should be promptly consulted.