Nodular itchy rash belongs to chronic inflammatory skin diseases, mainly characterized by intense itching and nodular damage, you can apply glycerine lotion, mometasone furoate cream, etc., and give systemic oral medication if necessary. 1. Glycerite lotion: Glycerite lotion can be used to relieve acute itchy skin diseases, and has a certain therapeutic effect on the itching symptoms of patients with nodular itchy rash. The use of glycerin lotion during the attack period can stop the itching and astringent effect. 2. Mometasone furoate cream: belongs to the local topical glucocorticoid, with anti-inflammatory, anti-allergic, anti-itching and reduce the role of oozing, and then improve the symptoms of patients with itchy nodular rash. 3. Oral medication: patients with nodular itchy rash can choose to take oral antihistamines, such as loratadine, cetirizine, etc., in order to reduce itching, and to ensure sleep. The above medications need to be used in strict compliance with the doctor’s instructions, and should not be used blindly. It is recommended that patients go to the hospital in time for early and regular treatment.