Polycystic ovary syndrome (PCOS) is polymorphic and heterogeneous, mainly characterized by hyperinsulinemia (HA), ovulation disorders, ovarian polycystic changes and infertility; the endocrine disorders of PCOS are characterized by excessive insulin secretion, high blood T levels, excessive E2, and increased LH/FSH ratio. The pathogenesis of PCOS in Chinese medicine is not unrelated to the liver, spleen and kidneys, and is caused by the production of phlegm and dampness, blood stasis and other pathological products, resulting in the dysfunction of the physiological axis of the kidney and the uterus. Gui Zhi Fu Ling Wan is a famous formula in “The Essentials of the Golden Horoscope”, which has the effect of warming the menstruation and dispersing cold, activating blood circulation and resolving stasis, and slowing down the accumulation of obstruction. Pharmacological studies have shown that the effectiveness of this formula is related to estrogen-like blood activating properties. Modern pharmacological studies have confirmed that blood-activating drugs can improve tissue microcirculation, dilate blood vessels, improve blood oxygen supply around the lesion and induce ovulation. The method of strengthening the spleen and resolving phlegm PCOS is not unrelated to phlegm-dampness and spleen deficiency. Cang Wei Gui Phlegm Tang, which has the function of strengthening the spleen and regulating the qi, resolving phlegm and removing dampness, is from Ye Tian Shi’s Complete Book of Female Medicine. By lowering insulin levels, regulating glucose and lipid metabolism and improving local IR of ovaries in PCOS patients, Cang Wei Gui Phlegm Tang reduces blood T levels, improves endometrial tolerance, restores ovulation and pregnancy. Clearing heat and draining the liver is an important factor in ovulation disorders in PCOS patients. Danmiao Yiyao San is derived from the formula of “Taiping Huimin and Pharmaceutical Bureau”, which added Danpi and Shanmiao to Yiyao San, also known as Jiawei Yiyao San, with the effect of draining the liver, strengthening the spleen and clearing heat. Danmiao Zhuangyao San has no significant improvement on fasting blood sugar, probably mainly by lowering fasting insulin to reduce IPA. While improving IPA, Danmiao Zhuangyao San can effectively improve lipid metabolism disorder, obesity and reduce ovarian volume and weight in P_COS rats. The core pathogenesis of PCOS is the failure of follicles to develop and mature, which is mostly blamed on “kidney deficiency” in Chinese medicine. The application of Nourishing Kidney, Clearing Heat, Dampness and Blood Stasis formula not only significantly improves the clinical symptoms of obesity and seat sores in PCOS patients, but also significantly reduces the blood T, FSH, LH, LH/FSH levels, and the FNG, FINS, HOMA-IR, 120 min postprandial glucose and insulin levels compared with those before treatment. Modern pharmacological studies have shown that herbs for tonifying the kidney and activating blood have the effects of improving blood circulation, adjusting lipid metabolism, improving IPA and enhancing insulin effect. Activating blood, nourishing kidney and clearing heat Kuntai capsule is composed of Shu Di Huang, Huang Lian, Bai Shao, Huang Fen, Gum and Fu Ling, which is a pure Chinese medicine preparation. Among them, Shu Di Huang and Agaricus components have the effect of invigorating blood qi and nourishing kidney qi, Fu Ling has the function of strengthening spleen and permeating dampness, while Shu Di, Huang Lian, Bai Shao and Scutellaria have all been shown to regulate the body’s glucolipid metabolism by improving IR. Kuntai capsule has an endogenous regulating effect on sex hormones in PCOS patients, which not only improves the endocrine indexes and significantly reduces the level of androgens, but also facilitates the growth of follicles, improves follicle quality and induces ovulation in PCOS patients with Kuntai capsule.