Dandruff can be associated with seborrheic dermatitis, scalp furuncles, scalp psoriasis, ringworm of the scalp, etc., and medications need to be chosen to treat the cause. Medications include tacrolimus cream, sulfur cream and tretinoin. 1. Seborrheic dermatitis: Seborrheic dermatitis can increase dandruff, and anti-inflammatory drugs such as tacrolimus cream and mometasone furoate ointment can be used. Ketoconazole lotion can be used in case of fungal infection. 2. Scalp furuncle: dandruff caused by scalp furuncle, in the treatment of the general external drugs, such as sulfur cream, ketoconazole lotion, selenium disulfide lotion and so on. 3. Scalp psoriasis: topical medications containing hormones are usually used, such as tretinoin application, or topical vitamin D3 derivatives such as calcipotriol and tacalcitol. If necessary, it can be combined with oral medications such as Avitamin A and methotrexate. 4. Tinea capitis: a disease caused by fungal infection of the scalp and hair, which may cause dandruff and itching at the same time. At this time you need to give antifungal treatment such as topical miconazole, ketoconazole ointment, oral itraconazole and other drugs. In addition, you need to cut the hair, pay attention to personal hygiene, to avoid infecting others. In addition, improper choice of shampoo or failure to wash the hair in time can also lead to the appearance of dandruff. Dandruff increased significantly, can not be improved after changing shampoo, generally related to pathological factors, it is recommended to receive timely examination and treatment in dermatology, the use of medication, follow the doctor’s instructions.