Breast nodules with blood flow signals are not yet able to determine the benign or malignant nature and do not necessarily require surgery. The presence of blood flow signals in breast nodules usually suggests that they are relatively rich in blood flow, which is common in clinics where cell growth is more active, and this situation also includes the possibility of some malignant nodules. In benign cases, surgery may not be necessary, but in malignant cases, surgery should be performed at an early stage. When breast nodules have blood flow signals, further diagnosis should be made, taking care to exclude the possibility of malignant lesions. Ultrasonography or direct surgical excision of the nodule for pathology is recommended to clearly diagnose the nature of the breast nodule, etc. Most of the benign nodules have less blood flow signals, and once blood flow signals are present, they should be taken seriously. Breast nodules with blood flow signals should be taken seriously, improve the relevant examinations in a timely manner, and comprehensively determine whether the nodule is benign or malignant, and then take targeted treatment to avoid delaying the condition.