GIST, or gastrointestinal mesenchymal stromal tumor, is a malignant tumor and belongs to the category of cancer. GIST can occur in the stomach, small intestine, colon and other digestive systems, and can be metastasized through the bloodstream, with the most common site of metastasis being the liver. The main clinical symptoms include abdominal pain, abdominal mass, nausea, etc., which will have different manifestations according to the patient’s own specific condition. Currently, the preferred treatment for gastrointestinal mesenchymal tumors is surgical resection, with open surgery, laparoscopic surgery and other surgical methods. In addition, drugs such as imatinib and sunitinib can be used in the treatment of patients with gastrointestinal mesenchymal tumor. If diagnosed with gastrointestinal mesenchymal tumor patients, it is recommended to actively adjust the mentality and cooperate with doctors for treatment.