There is no obvious contraindication to the composition of tonifying the spleen and yi intestine pill and liu wei di huang pill, there is no clear research to prove that there are adverse interactions between the two, it is recommended that it is best to be taken at certain intervals, in addition, the use of drug stacking, please under the guidance of a medical professional, in order to avoid any adverse reactions. 1. The efficacy of tonifying the spleen and intestines is to replenish the center of the qi (treating qi deficiency by replenishing the spleen), strengthen the spleen and stomach (restoring the functions of the spleen and stomach), and astringent the intestines to stop diarrhea (relieving diarrhea by enhancing the astringent function of the intestines). Clinically, it can be used to treat the symptoms of Spleen deficiency and diarrhea (diarrhea caused by weak function of the spleen), as seen in diarrhea and abdominal pain, abdominal distension and intestinal tinnitus. Its composition includes Radix Astragali, Radix et Rhizoma Ginseng, Radix et Rhizoma Sarcina and other herbs. Adverse effects are not clear, pregnant women are prohibited. Avoid eating spicy and greasy food during the period of taking the medicine, and abstain from smoking and limiting alcohol. 2. The efficacy of Liu Wei Di Huang Wan is to nourish yin and tonify the kidney. It can be used in the treatment of kidney yin deficiency syndrome, including dizziness, tinnitus, lumbar and knee weakness, hot flashes, night sweating (abnormal sweating after sleeping, but sweating stops after waking up), and spermatorrhea. Its composition includes Radix Rehmanniae Praeparata, Rhizoma Coptidis, Cornu Cervi Pantotrichum and other herbs. Adverse reactions and contraindications are not clear, avoid eating spicy and greasy food during the period of taking the medicine, abstaining from smoking and limiting alcohol. Although there is no obvious contraindication to the above composition of drugs, but still need to be used under the guidance of a doctor.