Mixed ground glass nodule 25mm is more likely to be malignant, but it is not certain, usually need to be through the pathological tissue results of the nodule to determine the benign or malignant mixed ground glass nodule. Mixed ground-glass nodules refer to nodules with both solid and ground-glass components, and this type of nodule is more likely to be malignant, especially if the nodule lesion is more than 8mm, the possibility of malignancy is particularly high, so it is recommended to do a puncture biopsy as soon as possible to clarify the nature of the nodule, in order to treat it as soon as possible. For mixed glass nodules of 25mm, even if the current pathology of the puncture biopsy is precancerous, it is generally recommended to perform surgery as early as possible to remove the nodule due to the high risk of cancerous transformation, and to follow up the patient closely after the surgery.