As with most diseases, the treatment of lower extremity atherosclerosis occlusive disease should also achieve early prevention, early detection and early treatment. To prevent and treat lower extremity atherosclerosis, we should pay attention to good habits such as giving up smoking and other bad habits, abstaining from high-fat indigestible and stimulating foods, eating a light diet, and eating more fruits and vegetables and legumes. Diabetes, hypertension and hyperlipidemia should also be actively treated. Patients diagnosed with this disease should not walk too fast to avoid the onset of ischemic symptoms, but appropriate walking exercises can be used to enhance the tolerance of lower limb tissues to ischemia, and to promote the formation and opening of collateral vessels around the occluded artery, which can play a role in alleviating the disease. Lower limb atherosclerosis occlusive disease such as cold feet should pay attention to insulation, but can not use hot water bags to warm the feet or soak feet with hot water, because this will aggravate the lower limb ischemia, making the condition worse. In addition, patients can also take some vasodilator drugs under the guidance of doctors to improve the blood circulation of the affected limbs. For patients diagnosed with lower limb atherosclerosis and occlusive disease, treatment such as improving living habits, lowering blood pressure, lowering lipids and antiplatelet aggregation as prescribed by internal medicine can slow down the progress of lower limb atherosclerosis and occlusion, but cannot fundamentally eliminate the narrowing and occlusion of existing lower limb arteries. Patients should still go to a vascular surgeon as soon as possible, and the main treatment method is to reconstruct the blood supply of the affected limb through surgery. Surgical procedures for lower extremity atherosclerosis include endovascular stripping, artificial vessel replacement, bypass reconstruction, and other traditional procedures, as well as endoluminal revascularization. In contrast, traditional surgery is very traumatic and risky, especially not suitable for patients with lower extremity atherosclerosis occlusive disease combined with serious cardiovascular and cerebrovascular disorders and diabetes mellitus. In contrast, endoluminal intervention in the arteries of the lower extremities has the advantages of being minimally invasive, simple, effective and repeatable, and is the direction of development in the diagnosis and treatment of vascular diseases. The procedure only requires a rice-sized incision at the root of the thigh, and the catheter, balloon and stent are inserted into the diseased artery to complete balloon dilation and stent placement in the narrowed and occluded artery site, and the patient can get out of bed the next day, thus saving the patient from the pain of open surgery. Currently, the following endovascular interventions for lower extremity atherosclerosis and occlusive disease are commonly used: percutaneous balloon angioplasty (PTA) of the lower extremity arteries and endovascular stenting of the lower extremity atherosclerosis and occlusive disease. Percutaneous balloon angioplasty (PTA) of lower extremity arteries is a major advance in the treatment of vascular diseases. The main mechanism of balloon angioplasty is to dilate and separate the stenosed and sclerotic intima, while destroying the smooth muscle elastic layer and collagen fibers of the intima, causing the atherosclerotic plaque to fracture and the intima to stretch. At present, with the emergence of new technologies and materials, PTA can also achieve satisfactory results for long segment occlusion of superficial femoral arteries and occlusion of arteries below the knee in patients with diabetic foot. While percutaneous balloon angioplasty of lower extremity arteries can lead to vascular entrapment tears and elastic retraction, lower extremity endovascular stenting overcomes the two major defects of PTA by stent implantation to squeeze the plaque and compress the vessel wall, and is a new endoluminal treatment for lower extremity atherosclerotic occlusive disease. One study found significant differences in outcomes between two groups of patients with lower extremity atherosclerosis occlusive disease treated with lower extremity atherosclerosis occlusive stent implantation and lower extremity atherosclerosis occlusive disease treated with PTA alone, respectively, and the results of 2-year follow-up showed that the former had a 10%-15% higher lower extremity atherosclerosis occlusive disease patency rate.