Atherosclerosis of the lower limbs is one of the most important causes of chronic occlusion of the lower limb arteries, with clinical manifestations such as pain, pulselessness, coldness, pale skin, intermittent claudication, resting pain, lower limb ulcers, necrosis, etc., which seriously affects the quality of life of patients. According to the severity of ischemic symptoms, lower limb atherosclerotic disease can be manifested as asymptomatic (refers to the lack of typical intermittent claudication symptoms), intermittent claudication (fatigue, discomfort, or simple pain confined to specific muscle groups of the lower limbs when walking), severe limb ischemia (resting pain and lower limb ischemic ulcers, necrosis, etc.), as well as acute limb ischemia (due to the atherosclerotic stenosis caused by the lower limb arteries acute thrombosis), etc.; Diagnosis Diagnosis: 1, color ultrasound: clearly show the lower limb artery stenosis or occlusion section of the lumen and wall conditions, advantages: convenient and non-invasive, shortcomings: the lesion is not enough sense of the whole, the results of the ultrasound by the ultrasound doctor’s technical level. 2.Magnetic resonance/CT angiography: to make a clear judgment on the degree and scope of stenosis of the lesion, there are some false positives. 3.Angiography: the gold standard for diagnosing arterial obstructive diseases, visualizing the location, shape, degree, cause of embolism, collateral circulation, distal branch blood flow and other conditions of arterial stenosis. However, it is an invasive test, and is now mostly used as a necessary test for endoluminal treatment. 4.Related physical signs and laboratory tests. Vascular treatment methods 1, surgery iliac, common femoral artery lesions surgical revascularization generally use artificial vascular bypass, the patient’s physical conditions require high, traumatic, long hospitalization time. 2, endoluminal intervention Balloon dilatation (PTA) and stent implantation is currently the most widely used endoluminal method. The doctor will insert a catheter with a diameter of about 2mm into the stenosis of the artery through the femoral artery, fill the balloon to release the stenosis, and place a stent to prevent the stenosis from retracting if necessary. Precise local treatment, small damage, avoiding major surgery, local anesthesia, no pain for the patient during the operation. 3, the efficacy of endoluminal treatment and surgery Randomized trials were conducted to evaluate whether surgical or endoluminal revascularization was performed. Holm et al. reported that for iliac artery and femoral N artery lesions, there was no significant difference between the two groups of patients when observed for 1-4 years. Conclusion The treatment of atherosclerotic occlusion of the lower extremities requires a combination of therapies from etiologic control, pharmacologic therapy, and revascularization. After the patient develops obvious symptoms, revascularization through surgery or endoluminal intervention is currently the most effective method, and endoluminal intervention replaces or supplements surgery to a large extent. Minimally invasive endoluminal intervention has become one of the main methods for lower limb atherosclerotic occlusive disease.