Platinum-based chemotherapeutic drugs often refer to cisplatin, carboplatin, oxaliplatin and other chemotherapeutic drugs, which may have gastrointestinal side effects, bone marrow suppression, kidney damage and other side effects. 1. Gastrointestinal side effects: nausea, vomiting, abdominal distension, indigestion and other gastrointestinal reactions are common and widespread side effects of platinum drugs, which often appear in the early stage of chemotherapy and gradually decrease after the end of chemotherapy. 2. Myelosuppression: myelosuppression such as leukopenia, hemoglobin decrease and thrombocytopenia is also one of the common side effects of platinum, and the myelosuppression of carboplatin is slightly more significant than that of cisplatin. 3. Kidney injury: proteinuria, creatinine elevation, decreased renal function and other kidney injuries are also one of the side effects of platinum drugs that need attention, especially cisplatin, nephrotoxicity is higher than other platinum drugs. In addition to the above side effects, platinum drugs may also have ototoxicity, peripheral nerve sensory abnormalities, liver function abnormalities and other side effects, and is prohibited for those who are allergic to it, and attention should be paid to hydration and diuresis in the process of cisplatin administration, and attention should be paid to the avoidance of cold and raw stimuli in the process of oxaliplatin administration. It is recommended that patients apply platinum drugs under the guidance of a doctor, and should not apply on their own.