More and more patients with coronary artery disease are treated with balloon dilatation or stenting. Some patients do not understand what to pay attention to after the interventional procedure, and postoperative adverse cardiac events such as sudden death, recurrent angina, recurrent myocardial infarction, and heart failure leading to re-hospitalization or re-intervention may occur due to discontinuation of medications, adverse reactions to medications, or failure to perform lifestyle management. Therefore, it is important to understand the issues associated with the post-procedure period. First of all, it is important to understand what kind of changes occur in the vessel after stenting. Nowadays, most of the stents used in the clinic are stainless steel or alloy skeletons, which do not contain high iron content, so there is no need to worry about not being able to undergo MRI due to stenting or even worrying about the influence of the magnetic field in the living environment on the stent, which will cause the stent to heat up or shift, with undesirable consequences. First of all, after stent placement, the local vascular endothelium will proliferate due to the stimulation of exophytes, and generally the drug stent will be wrapped by the proliferating endothelial cells in about 1 month, and the metal part will not be bare, and the stent will be able to prevent the endothelial cells from over proliferating and causing restenosis in the stent due to the continuous release of the local drug. And if the local dose of drug is too large or other factors cause the endothelium can not completely cover the metal part of the stent, it can also lead to rare thrombosis, resulting in myocardial infarction or sudden death. Clinical data of the latest generation of drug-eluting metallic stents show that the incidence of in-stent restenosis and in-stent thrombotic events within 1 year is low, ranging from about 0-5%, which is much lower than the incidence of 10-15% in the era of bare stents. In recent years, completely absorbable drug-coated polylactic acid stents, clinical research is still in progress, and currently only available free of charge for clinical research, although it can be completely absorbed and decomposed into water and carbon dioxide discharged out of the body, but there are some problems have not been solved, so now the use of drug-eluting metal stents is still recommended for clinical use. Secondly, stenting is mainly for severe coronary stenosis or thrombosis, plaque rupture, and cannot solve all the problems of coronary heart disease, especially if the coronary vessels without stent implantation also have other mild or moderate stenosis, drug therapy is more important. Medication is the foundation of coronary heart disease treatment and can likewise reduce long-term mortality in patients with coronary heart disease. Compared with no medication, antiplatelet drugs such as aspirin, clopidogrel or tegretol, plus statins can reduce the relative risk of patients with coronary heart disease by as much as 30-50%, but this effect may take 5-10 years, or even longer, to show, and adherence to the medication is critical. Of course, medications, including our daily diet, need to be metabolized by the liver and kidneys, and many patients are concerned that the addition of medications will increase the burden on the liver and kidneys and bring about liver and kidney damage. A large number of studies have also provided us with evidence showing that the total risk of adverse effects from these drugs is less than 5%, and the risk of fatality is even less than 1%. Therefore, doctors require that all patients with coronary artery disease should be followed up once every 1-3 months during the first year of taking the drugs, and once every 6 months to 1 year for those who do not have any adverse effects after one year and whose condition has stabilized, in order to monitor whether the drug dosage is up to the standard, whether the drug is effective, and whether the drug is working properly. The main purpose is to monitor whether the medication dose is up to standard, whether the medication is effective, whether there are any adverse reactions to the medication, and whether the medication can be maintained, changed, or discontinued. In addition, after the intervention, it is necessary to pay attention to blood pressure and heart rate, blood sugar and lipid levels, as well as smoking cessation. These four factors are also the most important factors affecting the prognosis of patients with coronary artery disease. Blood pressure and heart rate need to be stabilized. Depending on age, severity of coronary artery disease, and heart and kidney function, your doctor will recommend a target blood pressure and heart rate for your patient. If you do not know your target blood pressure and heart rate, you should consult your surgeon or an experienced doctor. Diabetic patients need to maintain fasting blood glucose below 7mmol/L and avoid hypoglycemic episodes. They should consult their surgeon and work with an endocrinologist to adjust their glucose-lowering drug regimen; diabetic patients’ diet and weight management are also very important, and can be used to assist in the treatment of diabetic patients. Lipids are of course the most important, domestic and foreign guidelines require patients with coronary heart disease to reduce LDL-C to the original baseline value of less than 50% or less than 1.8 mmol / L, statins are the basic drugs, lipids can not reach the standard can be considered to increase the amount of medication, choose high-intensity statins or add other types of lipid-lowering drugs; if lipids to reach the standard, statins need to be adhered to take, which can reduce the risk of plaque rupture and reduce the risk of cardiac arrest, and reduce the risk of cardiac arrest, and the risk of plaque rupture. If the blood lipid level meets the standard, statins should be taken consistently, which can reduce the risk of plaque rupture in blood vessels and reduce the risk of myocardial infarction, sudden death and stroke. China has a large population of smokers and a large number of people are threatened by secondhand smoke, and smoking has a very large impact on coronary heart disease. Compared with non-smoking patients, smoking can lead to endothelial damage, atherosclerotic plaque destabilization in blood vessels, and trigger a 5-7 times increase in cardiac events. Finally, regarding the management of patients’ lifestyles after intervention. Some patients think that stenting means that they have become complete “patients” and do not dare to be active; while others, once stented, suddenly become “athletes” and work out desperately, which is not the right approach. For patients with acute myocardial infarction after interventional therapy, we emphasize that exercise rehabilitation training for patients with coronary artery disease is based on cardiopulmonary function assessment, combined with the patient’s previous exercise patterns, guided by moderate-intensity activities, step by step, according to the amount of energy, aerobic exercise is the main focus, and regularly need to consult a professional doctor to conduct cardiopulmonary assessment, to prevent over-exercise or insufficient exercise. As for patients with stable coronary intervention and normal cardiac function, they can generally work normally and engage in general physical labor after discharge from the hospital. In terms of diet, it is advocated to control the quantity and quality of food, both by trying to choose different kinds of food intake daily and eating lightly, while paying attention to controlling the amount of food and avoiding overeating. Emotion management is also more important. Some patients with coronary artery disease may be depressed, irritable and insomniac after intervention for various reasons, which also triggers reoccurrence of chest tightness or even chest pain, and it is recommended to evaluate the corresponding indexes, and to add medication according to the degree of anxiety and depression. In conclusion, intervention is only part of the treatment of coronary heart disease, the above problems can not be included in every patient’s problems, if you have other problems, you can consult the relevant interventionalists or outpatient clinic, so that the doctor and you together to solve the problem.