Multiple small cystic low-density shadows in the head of pancreas may be multiple small cysts in the head of pancreas, which are benign lesions and can be followed up for observation; or they may be malignant tumors in the head of pancreas, which can be treated by surgery, radiotherapy and other methods. 1. Multiple small cysts in the head of pancreas: Multiple small cysts in the head of pancreas can be manifested as multiple small cystic hypodense shadows, which can be further examined by enhanced CT or enhanced MRI, etc. If the relevant examination considers it as multiple small cysts in the head of pancreas, it can be observed mainly, and reviewed and compared at 3~6 months, and then, if the review remains unchanged, it can be continued to be observed and reviewed and compared at 6~12 months. 2. Malignant tumor of pancreatic head: pancreatic head cancer with multiple metastases around the pancreatic head can also be manifested as multiple small cystic hypodense shadows in the head of pancreas, which is often accompanied by the elevation of CA199 and other tumor markers, and can be biopsied or surgically resected for pathological examination when suspected of malignancy, and supplemented with local radiotherapy and chemotherapeutic drugs such as gemcitabine and cisplatin to prevent local recurrence and distant metastasis after operation. Multiple small cystic hypodense shadows in the head of the pancreas is a simple imaging description, other tests are needed to clarify the type of the disease, and according to the specific circumstances of the choice of observation, surgery, or radiotherapy and other treatment options, it is recommended that the relevant patients under the guidance of a doctor for diagnosis and treatment.