Treatment methods for hepatic portal vein thrombosis mainly include targeted drug therapy, surgical resection, radiotherapy, etc. The specific treatment plan should be decided according to the actual situation of patients. 1. Targeted drug therapy: some patients have molecular targets of cancer thrombus, so they can be treated by taking molecular targeted drugs, such as sorafenib, lenvatinib and so on. 2. Surgical resection: For patients with less severe hepatic portal vein thrombosis, surgical resection, such as hepatectomy, can be adopted to achieve the therapeutic purpose. The survival rate of patients treated by surgical resection is higher. 3. Radiation therapy: Radiation therapy can help to downstage the tumor so as to reduce the size of the thrombus. Patients with hepatic portal vein thrombosis should go to regular hospitals as soon as possible and let doctors decide the treatment plan to avoid delaying the condition.