Liver cancer metastasized to vertebrae means liver cancer has metastasized and the site of metastasis is on the cone of vertebrae, which is subdivided into spine, thoracic vertebrae and lumbar vertebrae. The common symptom of patients with liver cancer metastasized to vertebrae is pain at the metastatic site, which is usually mild and intermittent, often failing to attract patients’ attention, and gradually becomes persistent and severe pain. Meanwhile, it may also lead to neurological dysfunction, such as leading to motor dysfunction will occur in one or more groups of muscle groups muscle weakness, and even paralysis in serious cases. If liver cancer is diagnosed to have metastasized to the vertebrae, patients should keep a good attitude and cooperate with doctors to formulate appropriate treatment plans according to their specific conditions, in order to relieve pain symptoms, improve or maintain normal nerve function and try to restore the structural integrity of the spine.