Stage IV decubitus ulcers are more serious and should be treated by avoiding continued pressure on the local tissues, using medication for anti-infection treatment when infection occurs, and removing the local necrotic tissues, and may also require surgery to close the wound. Patients with stage IV decubitus ulcers have a full layer of skin tissue loss, which is often deep enough to see bone and muscle, and should be treated to avoid continued pressure on the affected area, and if infection occurs in the wound, drugs such as cefoperazone and ceftriaxone should be used for anti-infective treatment. In addition, the local necrotic tissue should be removed, and then the local exposed trauma should be repaired in order to avoid infection of the exposed trauma. Repair of the localized skin may require removal of healthy skin from other areas, followed by skin grafting of the exposed wound. Stage IV decubitus ulcers take longer to heal and may take up to 3 months or even years to heal, and if the patient is in poor condition, the condition may persist for a long period of time.