Polycystic ovarian syndrome (PCOS) is an endocrine disorder syndrome in which reproductive dysfunction coexists with abnormal glucose metabolism. It is characterized by persistent anovulation or sporadic ovulation, multiple immature follicles, varying degrees of hyperandrogenemia, hyperinsulinemia and insulinresistance (IR), and abnormal lipid metabolism. The main clinical manifestations are menstrual sparing, amenorrhea, infertility, hirsutism, or acne, which are more common endocrine syndromes in women of reproductive age. the abnormal endocrine environment of PCOS predisposes to type 2 diabetes, gestational diabetes, centripetal obesity, hypertension, coronary heart disease, and other metabolic syndromes, as well as an increased risk of endometrial cancer. Although there is no name corresponding to polycystic ovary syndrome in ancient Chinese medical texts, according to its clinical manifestations, this disease is generally considered to belong to the categories of “amenorrhea”, “infertility”, “collapse and leakage” and “obstruction” in Chinese medicine. “The prevalence of PCOS is 5-10% in women of reproductive age, and up to 30%-60% in patients with anovulatory infertility. If not properly treated, it can affect women for the rest of their lives, so early detection and treatment is important for patients. The exact cause of PCOS is not well understood, but modern medicine believes that the dysfunction of the hypothalamic-pituitary-ovarian axis is one of the pathophysiological changes of PCOS, the cycle center of the hypothalamus is impaired, the positive and negative feedback of estrogen to the hypothalamus is abnormal, the hypothalamus releases luteinizing hormone (LH-RH) out of cycle, so that the follicle stimulating hormone (FSH) and luteinizing hormone (LH) released by the pituitary gland are out of proportion. The continuous secretion of LH without cyclic changes causes excessive production of androgens in follicular membrane cells, and LH peaks do not appear in the middle of menstruation, resulting in obstruction of follicular development and ovulation and polycystic changes such as follicular cysts and thickening of the envelope, and elevated LH stimulates the ovaries, causing disorders in the ovarian enzyme system, affecting the synthesis of estrone (E ) and estradiol (E2), and the synthesis of androstenedione ( A) and testosterone (T) accumulation in the body, resulting in increased plasma androgens, while androgens inhibit follicular maturation, making the developing follicles atretic and unable to discharge; FSH deficiency, LH to FSH ratio imbalance resulting in granulosa cells synthesizing estrogen without cycle and ovulation dysfunction are the causes of amenorrhea. Studies in the last decade have shown that there is IR in PCOS, and the compensatory response of pancreatic islet B cells to IR is to secrete too much insulin and develop hyperinsulinemia. Hyperinsulinemia promotes the secretion of androgens from two endocrine glands, the ovary and the adrenal gland, and both of these hormones can decrease the synthesis of sex hormone binding globulin by the liver. This causes elevated concentrations of free testosterone and estradiol, which increase LH secretion and symptoms of hyperandrogenism even more. According to TCM, the main cause of polycystic ovary syndrome is the imbalance of the relationship between the kidney, the punch and the uterus. The normal function of the reproductive system of women is mainly related to the function of the kidneys, the kidney is the root of menstruation and reproduction, the essence of the kidneys is the source of growth and development and reproduction, Chinese medicine has “the kidneys are the main reservoir of essence, the kidneys are the main source of reproduction”, “in the kidneys”, “menstrual water comes from the kidneys”. Insufficient kidney energy, deficiency of kidney essence, lack of fullness of the heavenly sperm, and emptying of the ramus, will lead to scanty menstruation, amenorrhea, and infertility; deficiency of the kidney will delay the arrival of the heavenly sperm, and polycystic ovary syndrome patients mostly develop soon after menarche, when the heavenly sperm first arrives and the kidney water is not yet full, just as the “Women’s Complete Good Recipe” says: ” The kidney energy is in full bloom, the flow of menstrual blood is in full flow, and the menstrual blood should go down at the right time, otherwise it will not pass. Summarizing the experience of medical practitioners over the ages, combined with the analysis of clinical symptoms, the pathogenesis of this disease is based on kidney deficiency, accompanied by phlegm and dampness, or blood stasis. Some doctors advocate the view that kidney deficiency leads to phlegm-dampness, and phlegm-dampness damages the kidney yang, and phlegm-dampness causes phlegm-dampness, which is detrimental to the essence of the essence and the uterus and the uterine veins, and affects the two sperms and causes infertility; phlegm-dampness and phlegm-dampness congests the uterus and obstructs the uterus, which leads to scanty menstruation and amenorrhea, but the clinical treatment is not effective only with the method of warming. Some doctors combined with modern medical theory, PCOS is due to hypothalamic-pituitary-ovarian gonadal axis dysfunction, excessive secretion of sex hormones, promoting excessive energy metabolism, the patient clinical evidence although no obvious kidney yin deficiency symptoms, but the body already exists in the hidden kidney yin deficiency. Clinical studies have shown that luteinizing hormone (LH) M follicle stimulating hormone (FSH) less than 2.5 or lower is mostly seen as kidney yin deficiency; those with LHMFSH greater than 2.5 are generally dominated by kidney yang deficiency. Modern pharmacological studies have shown that kidney tonics have estrogen-like effects and can regulate endocrine mechanisms, affecting the secretion of GnRH through the regulation of β-endorphins and 5-hydroxytryptamine in the brain, and regulating reproductive function; kidney tonics can also increase pituitary gonadotropin levels, increase LH/HCG receptors in the ovaries, improve ovarian responsiveness to pituitary gonadotropin, and increase endogenous estrogen levels, thus promoting the primary follicles to the dominant ovaries. This promotes the development of primary follicles to the dominant follicle, promotes follicular growth, development, maturation and discharge, and restores the menstrual cycle. In the first place, the “Danxi Xinfa Zizi” says: “If a woman is fat, she has a very thick endowment, she is wanton in eating and drinking, and her menstrual flow is not regulated, she cannot become pregnant, so it is called a body full of fat and overflowing, and the uterus is closed, so it is advisable to take a bath of phlegm. The Ming Dynasty “Wan’s Women’s Section” also has a similar description of the disease: “but they are fat, full of fat, the door of the first chamber does not open, holding phlegm, phlegm and saliva congestion, blood waves do not flow, so there is the expiration of the period and the first line, or a few months and a line and for turbidity, for the band, for menstrual closure, for the disease of childlessness.” Chinese medicine believes that “phlegm is always in the kidney”, “the spleen is the source of phlegm, the kidney is the storage of phlegm”. The spleen is responsible for the transportation of water and dampness, the spleen is deficient, the transportation is not regulated, the water is not distributed and stays in the body, coalescing into phlegm. When phlegm and dampness are stagnant, the flow of Qi is not smooth, and the flushing of the body is blocked, resulting in irregular menstruation and infertility; when phlegm and saliva are congested and overflowing with fat, the body becomes obese; when phlegm and dampness are sticky, they are most likely to block the flow of Qi, and when Qi is stagnant, blood is stagnant; when phlegm and dampness are intertwined with Qi and blood, they become obstruction, so the ovaries are polycystic and enlarged. In the book of “The Standard of Treatment for Women”, it is said that “the obstruction of the mass in women is a blood disease …… and the stagnation of blood and stagnation of blood makes it a mass”, and in the book of “Jin Yin”, it is said that “there is no drink in the mass, and there is no phlegm in the blood and stone obstruction. “. Obesity is one of the main symptoms of polycystic ovary syndrome, and about more than half of the patients with polycystic ovary syndrome are more obese, which is considered by Chinese medicine as phlegm and dampness within. Clinical studies have confirmed that obesity has a direct impact on sex hormone abnormalities in PCOS: 1.5% of androstenedione is converted to estrone and only 0.15% of testosterone is converted to estradiol in the conversion of sex hormones around normal menstruating women; and the adipose tissue in obese PCOS patients becomes the main base for continuous production of estrone, which produces abnormal regulation of both intraovarian and gonadal axis. Therefore, many medical practitioners believe that the pathogenesis of polycystic ovary syndrome is based on phlegm-dampness, and since Zhu Danxi, more medical practitioners have discussed this disease from the perspective of phlegm-dampness. The occurrence of this disease is also related to kidney deficiency and blood stasis. The kidney is the main water, the normal function of the kidney, the opening and closing of the normal water metabolism, the smooth flow of Qi, then the stasis to go through; kidney Qi deficiency, dysfunction of the internal organs, can not transform the Qi to move water, gathered and wet, wet blocking the Qi, Qi stagnation, blood stasis, stagnation of the cell veins, resulting in menstrual disorders, menstrual water thinning or amenorrhea. In recent years, some medical practitioners believe that the onset of this disease is also closely related to liver depression. Stagnation of liver qi leads to derangement of the flow of Qi and deregulation of the flushing process, resulting in menstrual disorders, infertility, acne and hirsutism. In conclusion, the etiology of polycystic ovary syndrome is closely related to the kidney, spleen and liver, among which kidney deficiency is the key to its development. All of them belong to the category of phlegm-dampness and blood stasis. Therefore, it is believed that PCOS has kidney deficiency as the root of the disease, phlegm-dampness and blood stasis as the symptoms of the disease, and the pathological characteristics of the disease are deficiency of the root and the symptoms of the disease, and the combination of deficiency and reality.