The main causes of pain in the back of the pancreas include exudation of the pancreas itself and radiating pain. 1. Exudation from the pancreas itself: pancreatic diseases can cause blockage and narrowing of the pancreatic ducts and inflammatory exudation or pancreatic fluid spillage, while the pancreas itself is located in the epigastric region and in the posterior part of the abdominal cavity, which belongs to the retroperitoneal organs. When the inflammatory exudate or pancreatic fluid invades the peritoneum and retroperitoneal tissues, it stimulates the peritoneal nerves and causes back pain. 2. Radicular pain: pain caused by intra-abdominal organ disease will involve certain body parts in pain, clinically called radicular pain. The mechanism is due to the fact that the pathway responsible for uploading visceral nociceptive nerves to the cerebral cortex after visceral disease shares a spinal cord segment with the corresponding nerve pathway that innervates cutaneous body surface pain. Radiating pain in pancreatic disease tends to appear on the left side of the back. If the patient has severe symptoms of pain in the back of the pancreas, or if the symptoms persist without improvement, he or she should go to the hospital for treatment.