TAF refers to Tenofovir disoproxil fumarate tablets, the decrease of hepatitis B surface antigen after taking Tenofovir disoproxil fumarate tablets is a phenomenon of gradual improvement of the condition, which is a normal situation. Propofol Tenofovir Fumarate Tablets, the main ingredient of which is Propofol Tenofovir, is suitable for the treatment of people over 12 years of age suffering from chronic hepatitis B. It belongs to a kind of nucleotide analogs in antiviral drugs. These drugs can directly inhibit the virus and rapidly reduce the viral load, while the surface antigen of hepatitis B patients can indirectly reflect the load of hepatitis B virus in the body, and the lower the surface antigen is, the better. The lower the surface antigen, the better. When the surface antigen decreases, it indicates that the condition is gradually improving. Patients taking Tenofovir disoproxil fumarate tablets may have adverse reactions such as abdominal pain, diarrhea, skin edema, etc. It is prohibited for those who are allergic to the ingredients of the drug as well as for children under the age of 12 years, and should be used with caution in pregnant women as well as breastfeeding patients. If the surface antigen decreases after taking tenofovir disoproxil fumarate tablets, it means that the load of hepatitis B virus gradually decreases in the body, and the patient should follow the doctor’s instructions to insist on taking the drug for treatment. If any adverse reaction occurs during the period of taking the medicine, you should go to the hospital for examination and treatment.