Discomfort in the throat when quitting smoking may be caused by pathologic changes in the mucous membrane, or it may be a normal withdrawal reaction. If the patient is a long-term smoker, the mucous membrane of the throat may undergo pathological changes when stimulated by harmful substances in tobacco for a long time. This pathologic change is generally mucosal congestion, hyperplasia, increased secretions and other manifestations, patients often cough, cough sputum, foreign body sensation in the throat and other symptoms, and some patients may even develop into irritating chronic pharyngitis. Long-term smoking patients, the body will have a certain dependence on nicotine in cigarettes, when the sudden stop inhaling nicotine will lead to psychological or physical withdrawal symptoms, one of the withdrawal symptoms is that you will feel uncomfortable throat, some patients may also experience depression, irritability, anxiety and other emotions or chest tightness, nausea, vomiting and other discomforts. If it is a normal withdrawal reaction, it will gradually reduce with the time of quitting smoking, if the discomfort in the throat lasts for a longer period of time, it is recommended that the patient go to the hospital in time to prevent the occurrence of pharyngeal lesions.