Diseases that cause enlarged thyroid neck include non-toxic goiter, hyperthyroidism, thyroiditis, etc. Each disease has different treatment methods. 1. Non-toxic goiter: This includes diffuse non-toxic goiter and non-toxic multinodular goiter. Diffuse non-toxic goiter can be eliminated by improving iodine nutritional status, and if necessary, surgery; non-toxic multinodular goiter can be eliminated by thyroxine treatment, surgery or radioiodine treatment. 2. Hyperthyroidism: it can be treated with drugs such as propylthiouracil and methimazole, etc. Surgery or radioiodine treatment is feasible when it is ineffective. 3. Thyroiditis: including subacute thyroiditis, autoimmune thyroiditis and painless thyroiditis. Subacute thyroiditis can be treated with aspirin, ibuprofen and other non-steroidal anti-inflammatory drugs in mild cases, and prednisone in severe cases; autoimmune thyroiditis can be treated with levothyroxine for goiter; and painless thyroiditis is generally not a problem that requires special treatment, and the lesions are reversible. When the thyroid neck is enlarged, please go to the hospital for a clear examination to determine the cause of the disease and timely treatment.