Hepatitis B can be transmitted to a spouse through sexual contact. Hepatitis B is transmitted through blood and body fluids. It has been confirmed that semen, vaginal secretions, breast milk and other body fluids contain the hepatitis B virus, but certain conditions must be met for transmission. Hepatitis B surface antibodies are protective antibodies. If the titer of hepatitis B surface antibodies in the spouse is strong enough, he/she can avoid being infected. The infectiousness of a hepatitis B patient is related to the DNA load of the hepatitis B virus in the body, and the higher the hepatitis B DNA load, the more infectious it is. Therefore, it is recommended that the hepatitis B patient and spouse should have regular laboratory tests, the spouse should be vaccinated against hepatitis B according to the test results to ensure that the hepatitis B surface antibody in the body is at a high level, and the hepatitis B patient should reduce the infectiousness through treatment.