Aminoglucose, or glucosamine, may irritate the stomach, and the drug can cause transient and mild gastrointestinal side effects such as nausea and heartburn. Glucosamine can be used for osteoarthritis in all parts of the body, such as the hip and knee joints, as well as the spine, wrists, hands, shoulders, and ankles, to relieve and eliminate the symptoms of osteoarthritis, such as pain and swelling, and to improve joint mobility. This medication is well tolerated, with occasional mild gastrointestinal disturbances such as nausea, heartburn, and diarrhea, as well as dizziness and allergies. It is advisable to take it with or after meals to minimize gastrointestinal discomfort, especially in patients with gastric ulcers. It is contraindicated for those who are allergic to the product, allergic persons, persons with severe hepatic and renal insufficiency, pregnant and lactating women should be cautious. If symptoms are not relieved after one course of medication, consult a physician or pharmacist. Glucosamine needs to be used strictly under the guidance of a professional physician to maximize its efficacy. After the occurrence of gastrointestinal side effects, it is necessary to consult a doctor in time and follow the doctor’s instructions for further treatment.