A hard lump on the face is considered to belong to acne, epidermal cysts, etc. It is necessary to clarify the cause of the disease, and then use the appropriate drugs for treatment, as follows: 1. Acne: for mild to moderate acne, topical retinoids can be used, such as adapalene gel, retinoic acid cream, etc.; for inflammatory lesions, topical benzoyl peroxide can be used to treat them; generally can also be combined with topical antibiotic medication, such as clindamycin gel, etc.; if the condition is serious and there is obvious inflammation, oral retinoids, antibiotics and other medications can be used to treat the condition. 2. Epidermoid cysts: Epidermoid cysts can be removed by surgical treatment. If the epidermal cysts are associated with infection, they can be treated with topical antibacterial drugs, such as erythromycin ointment, mupirocin ointment, etc., and can also be injected with glucocorticosteroids, such as trimethoprim, etc., and then local surgical excision can be performed after the inflammation subsides. It is recommended that patients with hard bumps on the face go to the dermatology department of the regular hospital in a timely manner, after a clear diagnosis of reasonable medication, not blindly self-medication.