There is no such thing as the most effective way to regulate the lack of sweating. The lack of sweating can be caused by blocked sweat glands, low basal metabolic rate, and underdeveloped sweat glands. Under the guidance of the doctor can be through vitamin drugs, thyroid hormones, vitamins and other drugs to regulate. 1. Sweat glands blockage: due to the sebaceous glands secretion, caused by sweat glands blockage, the condition of not sweating, can be relieved by vitamin drugs such as vitamin A, vitamin B6 tablets and so on. 2. low basal metabolic rate: if there is hypothyroidism patients, will make the metabolism slow, resulting in less consumption, causing low basal metabolic rate, the symptoms of not sweating, can be adjusted through the thyroid hormone class, thiourea and other drugs, levothyroxine sodium tablets, propylthiouracil tablets and so on. 3. Undeveloped sweat glands: the lack of sweating may be caused by undeveloped sweat glands, even if the metabolic rate is very high, due to the undeveloped sweat glands, it is easy to appear the phenomenon of not sweating. You can use vitamins and other drugs externally to regulate, such as clomipramine hydrochloride tablets or applying vitamin E ointment. Patients who experience no sweating should go to the hospital in time for proper treatment and therapy under the guidance of the doctor.