There are many reasons for ankle pain, the common ones are trauma, infection, arthritis and tendonitis, etc. General treatment, physical therapy, medication and surgery can be given to address the causes. 1. Trauma: In the acute stage of ankle trauma, braking and local cold compresses are needed; in the relieving stage, local hot compresses can be applied, the affected limb can be elevated, and non-steroidal anti-inflammatory drugs such as diclofenac sodium can be used to relieve the pain; for tendon rupture or bone fracture, external fixation or internal fixation can be given according to the seriousness of the disease. 2. Infection: common bacterial infection, local redness, swelling, heat and pain and other symptoms, need to give amoxicillin, levofloxacin and other antibacterial drugs, pain is obvious, can also give ibuprofen and other painkillers. 3. Arthritis: common osteoarthritis, rheumatoid arthritis, etc., can be given diclofenac sodium and other non-steroidal drugs, if necessary, can also be given to prednisone and other glucocorticosteroid drugs, gouty arthritis in the acute stage of colchicine treatment, remission of phenylbromarone and other uric acid-lowering drug therapy. 4. Tendonitis: aseptic inflammation, in addition to the use of ibuprofen and other anti-inflammatory pain medications, can also be combined with local hot compresses or lidocaine, trimethoprim and other drugs local closed injection treatment. It is recommended that patients go to the hospital, improve the auxiliary examination, in order to clarify the condition, the drug needs to be used under the guidance of a professional physician.