Breast ulceration in patients with plasma cell mastitis is a sign that it has become more severe, and the ulceration helps the pus to drain from the breast. Plasma cell mastitis is an inflammatory disease of the breast that often occurs during the non-lactating period. Patients may experience localized breast pain, redness, swelling and inflammation, and in some cases, breast discharge. As the disease progresses, the inflammation gradually worsens, causing the local skin of the breast to break down and flow pus, which is beneficial for the drainage of pus, but the wound should be carefully disinfected. Plasma cell mastitis can be treated with antibiotics such as amoxicillin and levofloxacin under the guidance of a doctor. Some patients can also apply drugs such as rifampicin for treatment. If the skin is ulcerated, patients can use drugs such as povidone-iodine to apply disinfection, pay attention to local hygiene to avoid infectious conditions, and in serious cases, the lump can be removed by excision surgery. Plasma cell mastitis should go to the hospital for treatment in time to avoid aggravation of the condition. The use of drugs need to be under the guidance of the doctor.