There is a feedback mechanism for thermoregulation, and it is a negative feedback regulation. The mechanism of thermoregulation is that sweat glands, skin blood vessels, skeletal muscles and endocrine glands are stimulated, and the information is transmitted to the hypothalamic thermoreceptors, which receive the information, sense that the external temperature is too high or too low, and control the heat production or dissipation, and regulate the body temperature accordingly. Sweat glands, skin blood vessels, skeletal muscles, endocrine glands and other receptors can increase or decrease the secretion of sweat glands and endocrine glands, skeletal muscles tremble, and skin blood vessels constrict or dilate to make heat production or heat dissipation. When the body temperature is abnormal, i.e., the level of the thermoregulatory center increases or decreases, and if it does not recover itself, it is necessary to consult a doctor.