The claim that five kinds of people should not drink coffee is not true. Coffee as a common drink, does not have a drug contraindication crowd, but usually, children, pregnant women, elderly women, osteoporosis patients, patients with cardiovascular disease, gastrointestinal diseases should be based on their own situation to properly control the intake of coffee. 1. Children: children are in the stage of growth and development, the body tissues are not yet fully developed, a large amount of coffee may make the central nervous system over-excited, the children’s memory. 2. Pregnant women: Pregnant women may experience nausea, vomiting and rapid heartbeat after drinking large amounts of coffee, and if a large amount of caffeine is absorbed by the fetus, it may affect the development of the fetus to a certain extent. 3. Elderly women: the body tissues of this group of people are in a state of degeneration, and the calcium needed in the body will increase, but coffee will increase the loss of calcium from the urine and reduce the calcium in the body. 4. Osteoporosis patients: Coffee will reduce the calcium in the body, osteoporosis patients should not drink a lot of coffee. 5. Patients with cardiovascular disease: the caffeine in coffee can lead to an increase in heart rate, and if patients with cardiovascular disease drink a lot of coffee, it may cause discomfort. 6. Patients with gastrointestinal diseases: the caffeine in coffee can stimulate the gastric mucosa and secrete too much gastric acid, which may lead to acid reflux and belching. Therefore, you should drink coffee in moderation to avoid excessive intake causing discomfort.