Sodium valproate is an antiepileptic drug belonging to the antiepileptic drugs, oral drug 1~4 hours blood concentration reaches the peak, the effective blood concentration is 50~100ug/ml.
Oral drug absorption is good, bioavailability is high, 1~4 hours blood concentration reaches the peak, the effective blood concentration is 50~100ug/ml.
With the increase of blood concentration, it will increase the concentration into the brain tissue, the drug half-life is 7~10 hours, mainly distributed in the extracellular fluid and liver, kidney, intestinal tract and brain tissue.
Most of the drug is metabolized by the liver, excreted by the kidneys, a small amount is excreted in the feces, and can be excreted through the placenta as well as breast milk.