Smelly feet can be caused by poor hygiene habits, wearing non-breathable shoes for a long time, and ringworm of the feet. Povidone-iodine has the ability to disinfect and kill bacteria, and applying povidone-iodine to the feet can assist in removing foot odor. However, povidone-iodine cannot kill fungi and cannot treat fungal foot odor. Excessive sweating of the feet, inducing bacteria, fungi breeding, disease-causing microorganisms decomposition of foot sweat, shedding of epidermal keratinocytes, keratin, will produce obvious odor. Povidone-iodine is a commonly used clinical disinfectant that can be used for a wide variety of disinfections as well as for skin disinfection. Excessive sweating of the feet, parasitic bacteria, you can use povidone-iodine on the local application, can play a role in killing bacteria-causing, can assist in the treatment of foot odor. However, fungal infections caused by foot odor, foot odor symptoms are more obvious, in addition to pay attention to personal hygiene, wash your feet diligently, the use of iodine povidone for disinfection, but also to the hospital dermatology, combined with the doctor’s advice, given ketoconazole, miconazole nitrate ointment topical application. If necessary, with oral antifungal drugs, such as itraconazole capsules for treatment. Please strictly follow the doctor’s instructions, do not self-medication.