Patients who are unable to hold their urine are advised to identify the cause before going for treatment. Generally, this symptom is caused by cystitis, urethritis, prostate enlargement and other diseases, which can be treated by drugs, surgery and other ways. 1. Cystitis: patients with cystitis, mainly due to urinary tract infections caused by the emergence of cystitis, patients will have frequent urination, urinary incontinence performance. Cystitis or patients can use drugs for treatment, such as ofloxacin, ciprofloxacin. 2. Urethritis: Urethritis is caused by infection. After the appearance of urethritis, the patient will have urinary urgency, accompanied by the symptoms of urination difficulties. Urethritis can be treated with antibacterial drugs such as ceftriaxone. 3. Prostatic hyperplasia: Prostatic hyperplasia caused by lower urinary tract obstruction can lead to urinary effort when serious, full urinary incontinence, unable to hold urine. Can use finasteride, tamsulosin, doxazosin and other drug treatment; can also apply transurethral resection of the prostate and other surgical treatment. The specific choice of which treatment should be carried out in accordance with medical advice.