Atrioventricular junctional pre-systole should have different treatments according to different causes, which may be caused by organic heart disease, electrolyte disorders, anemia and so on, and can usually be treated with drugs. 1. Organic heart disease: you can use antithrombotic drugs under the guidance of a doctor, such as aspirin, clopidogrel, etc., which can reduce myocardial oxygen consumption, you can also use beta-blockers, angina relief drugs, such as isosorbide mononitrate, with lipid regulation, plaque stabilization effect. 2. Electrolyte disorders: Concentrated sodium chloride, concentrated potassium chloride, magnesium sulfate, calcium gluconate, phosphate and other drugs can be used under the guidance of the doctor to correct the extracellular fluid hypotonic state and replenish blood volume. 3. Anemia: drugs such as iron dextrose, ferrous gluconate, iron sorbitol, ferrous fumarate, etc. can be used under doctor’s guidance, which can supplement the elements or factors needed for hematopoiesis. The symptoms of atrioventricular junctional pre-systole, it is recommended to do further examination under the guidance of a doctor, to clarify the cause of the disease and active treatment, and the use of drugs need to follow the doctor’s instructions.