Medical glue has poor impact resistance, slow degradation, sticking wounds will cause scarring of wounds, damage to the skin, bond strength is not enough. 1. Wound scarring: medical glue is generally used to bond tissues, or smaller wounds, the prolonged use of medical glue will cause abnormal skin breathing, damage to the skin, wound healing will be the symptoms of scarring. 2. Skin damage: gluing wounds may cause skin damage, due to the patient’s sensitivity to medical glue, poor breathability, localized rashes or skin abnormalities after use, blistering erosion, allergic dermatitis and so on. 3. Bonding strength is not enough: due to the increase in molecular weight, the bonding strength will increase, the molecular weight reaches a certain value and the adhesive is equal to the destruction, will make the bonding force decline. Medical adhesive wounds have advantages and disadvantages, the specific use should be based on their own situation, choose the right one for themselves.