Upright hypotension cannot be completely cured, but with active treatment, recurrent episodes can be avoided. Upright hypotension is mostly related to autonomic dysfunction, the specific cause of which is still unclear, and is mostly seen in elderly patients. Upright hypotension can not be completely cured, and then we should actively look for the triggers, and if there is a clear cause, we should actively remove the triggers. Patients who do not have a clear cause but have recurrent episodes of upright hypotension should be actively treated to avoid recurrent episodes. Patients with upright hypotension should avoid sudden standing, strengthen the exercise of vascular function, and wear compression stockings if necessary, which can reduce the attack of upright hypotension. Patients with upright hypotension should go to the hospital in time to find the cause of the disease under the guidance of the physician and give targeted treatment.