Metastasis of esophageal cancer to bone is usually the advanced stage of esophageal cancer, and tumor cells can be transferred to distant tissues and organs through lymphatic vessels and blood system. Esophageal cancer is a malignant tumor of epithelial origin in the esophagus. If esophageal cancer occurs to metastasize to bone, it is generally an indication of poor prognosis and belongs to advanced stage of esophageal cancer. Tumor cells of esophageal cancer mostly metastasize to distant tissues as well as organs through lymphatic vessels and blood system. If bone metastasis occurs, the symptoms mainly show pain at the bone metastasis, difficulty in swallowing and weight loss. It should be noted that if esophageal cancer patients develop bone metastasis with symptoms of bone pain, radiotherapy can be adopted according to doctor’s instruction, which can relieve the pain of bone metastasis and prevent pathological fracture. Meanwhile, chemotherapy, targeted therapy and other auxiliary treatments can also be adopted. For patients whose esophageal cancer has metastasized to bone, they need to take more rest in daily life and develop good habits of work and rest. Have a balanced diet and supplement more nutrition. Quit smoking and drinking and keep a good mindset.