Fenle and Sainen are both trade names of drugs, both generic name is hydroxychloroquine sulfate tablets, the overall efficacy of the drug and side effects are not significantly different, only Fenle hydroxychloroquine sulfate tablets and Sainen hydroxychloroquine sulfate tablets specifications are slightly different, and the indications of the manual are also slightly different. In terms of specifications, there are two kinds of specifications: 0.1g and 0.2g for each tablet of Fenroe Hydroxychloroquine Sulfate Tablets, while there is only one kind of Hydroxychloroquine Sulfate Tablets of 0.2g for each tablet of Sanen. In terms of indications, the indications of Fenle Hydroxychloroquine Sulfate Tablets only include systemic lupus erythematosus and cutaneous lupus such as discoidal erythema, while Sanen Hydroxychloroquine Sulfate Tablets are also clearly labeled as a treatment for rheumatoid arthritis and chronic arthritis of adolescents, in addition to lupus. Although there is a slight difference in the indications in the instructions, because the two active ingredients are the same, there is no clear distinction in clinical application that only Sanen Hydroxychloroquine Sulfate Tablets can be used for the treatment of arthritis. Adverse reactions such as visual field defects, diarrhea, anorexia, cardiac conduction abnormalities, and vertigo may occur with the use of hydroxychloroquine sulfate. Hydroxychloroquine sulfate is contraindicated in patients with known hypersensitivity to 4-aminoquinolines, in patients with pre-existing macular disease of the eye, and in children under 6 years of age. CAUTION: An ophthalmologic examination should be performed in all patients prior to long-term treatment with this product and annually thereafter. It is recommended that hematologic tests should be performed periodically with the use of this product, and the product should be discontinued if abnormalities occur. Whether it is Fenle Hydroxychloroquine Sulfate Tablets or Sainen Hydroxychloroquine Sulfate Tablets, it should be used under the guidance of a specialist, and should not be used on its own.