Vulvar itching after menopause may be atrophic vaginitis, cervicitis, non-specific vulvovaginitis, etc., usually local or systemic use of antibiotic drugs. 1. Atrophic vaginitis: after menopause, estrogen level will decrease, the vaginal wall cell atrophy, the PH value in the vagina will also increase, especially easy to cause germs to enter the vagina to trigger inflammation, you can follow the doctor’s instructions to apply estriol ointment, you can also use local antibiotics to inhibit bacterial growth, such as metronidazole, norfloxacin preparations. 2. Cervicitis: Decreased immunity, lack of attention to personal hygiene, bad sex will lead to inflammation of the cervical area, inflammation stimulation will increase the secretion, there will also be vulvar itching. If it is Neisseria gonorrhea infection, you can use cefixime and cefazoxime as prescribed by the doctor, if it is Chlamydia trachomatis infection, you can use doxycycline and minocycline as prescribed by the doctor, and if it is Mycoplasma genitalium infection, you can use azithromycin or moxifloxacin as prescribed by the doctor. 3. Non-specific vulvovaginitis: this disease is physical or chemical and other non-pathogenic factors leading to inflammation of the vulvar skin and mucous membranes, you can follow the doctor’s instructions to use povidone iodine or potassium permanganate sitz baths, and after the sitz baths apply antibiotic ointment, such as erythromycin ointment, fusidic acid ointment and so on. All of the above medications should be used under the guidance of a doctor, avoid self-medication. If there is any other discomfort, it is recommended to go to the hospital in time and follow the doctor’s instructions to deal with the treatment.