Numbness and swelling of the hands at night after working during the day may be due to overwork, cervical spondylosis, rheumatism. 1. Excessive fatigue: engaged in manual labor, carrying heavy objects or carrying during the day, will lead to excessive fatigue of the hand muscles, numbness and swelling at night when resting. 2. Cervical spondylosis: when suffering from cervical spondylosis, it will lead to compression of nerves in the cervical vertebrae, thus causing pain and numbness at the end of the limbs, and this symptom will usually be aggravated after labor. 3. Rheumatism: rheumatoid arthritis can also lead to numbness and swelling in the joints of the hands at night after working during the day, and some of them will also be accompanied by strong pain. Numbness and swelling of the hands at night after working during the day may also be due to other diseases, and should be promptly examined in the hospital to clarify the cause.