Normal people already experience a drop in blood sugar when they feel hungry, and the level of insulin secretion is also decreased, which is a relatively normal physiological response. In some patients, the drop of blood sugar when hungry and the abnormal increase of insulin secretion will aggravate the attack of hypoglycemia when hungry. The symptoms of hypoglycemia are manifested as palpitations, sweating, hunger, hand trembling, dizziness and other symptoms of hypoglycemia, and in severe cases, coma can occur. It is common in the following diseases: 1. Patients with weak constitution and poor eating are prone to severe hypoglycemia during starvation, which should be dealt with by improving eating and strengthening nutrition. 2. Islet beta cell tumor, which is a tumor formed by pancreatic beta cells and excessive secretion of insulin leads to hypoglycemia, which requires surgical treatment after diagnosis. 3. In the early stage of diabetes, insulin secretion and blood sugar changes are not synchronized. When blood glucose is falling, excessive insulin secretion will also produce hypoglycemia, and oral medication is needed for intervention treatment.