Symptoms of mitral tricuspid regurgitation of the heart are related to the severity. Mild regurgitation can be asymptomatic, while severe regurgitation can lead to heart failure, with symptoms such as dyspnea and lower limb edema. Mitral tricuspid regurgitation is most commonly seen in valvular lesions, which can lead to valvular insufficiency and regurgitation of blood when the heart contracts. A small amount of regurgitation has little effect on cardiac function, and patients may have no obvious clinical manifestations and do not require treatment. A large amount of regurgitation in the mitral tricuspid valve can lead to heart failure. A large amount of regurgitation in the mitral valve mainly leads to left heart failure, with pulmonary edema and dyspnea as typical clinical manifestations. A large amount of regurgitation in the tricuspid valve may appear right heart insufficiency, manifested by the venous system of stasis, such as lower extremity edema, abdominal effusion, pleural effusion, etc., the disease can also appear in the advanced stage of the symptoms of dyspnea. Mitral tricuspid regurgitation has obvious differences in the impact on the heart at different times, usually pay attention to strengthen the physical examination, cardiac insufficiency should be treated in time, if necessary, for valve replacement therapy. If there is any discomfort, we should consult the doctor in time to avoid delaying the condition.